منابع مشابه
Homer William Smith
This anthology commemorates a most unusual and complex person. Homer William Smith was best known as a renal physiologist whose work ranged from the evolution of the kidney to clinical studies on renal function and disease in man. He also studied and wrote about religion and philosophy, and published two novels, one of which, Kamongo, had rather a surprising success considering that its "plot" ...
متن کامل2008 Homer W. Smith Award: insights into the pathogenesis of polycystic kidney disease from gene discovery.
Polycystic kidney diseases (PKD) are a group of inherited disorders characterized by morbidity-associated development of renal cysts. Three forms of PKD are described here: The common, late onset, autosomal dominant PKD (ADPKD); the mainly infantile, autosomal recessive PKD (ARPKD); and the lethal, syndromic, Meckel syndrome that also includes central nervous system and digital defects. Positio...
متن کاملThe legacy of Homer W. Smith: mechanistic insights into renal physiology.
In 1945, Homer W. Smith published an article in the JCI that clearly demonstrated that para-aminohippuric acid is the most suitable agent for the evaluation of renal plasma flow in both humans and dogs; in addition, the paper provided detailed methodology that is still in use today. This paper is but one of many outstanding works performed by Smith and his colleagues that clearly established th...
متن کامل2015 Homer W. Smith Award: The Podocyte from Periphery to Center Stage.
This overview summarizes selected major developments over the last 40 years in understanding podocyte biology and its involvement in glomerular disease subjectively from my perspective. Serendipity has played a major role in my contributions to investigative nephrology that range from basic mechanisms of immune deposit formation in experimental membranous nephropathy to the role of a microRNA i...
متن کاملHomer W. Smith Award lecture. The juxtaglomerular apparatus: from anatomical peculiarity to physiological relevance.
Homer Smith died in 1962, the year before I started my career in the Department of Physiology of the University of Goettingen. At that time, his original work was still well known and widely quoted. Several decades later, this has of course changed, and the newer generation of renal physiologists and nephrologists is often unaware of who Homer Smith was and what he did. This is not totally surp...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1996
ISSN: 0085-2538
DOI: 10.1038/ki.1996.217